Ed Yong's ENCODE: the rough guide to the human genome explains for the general reader big news in science this week, namely ENCODE. But at the Finch and Pea they've got some tasty morsels too:
… at least from my perspective. I’ll now stop ranting about the hype and media coverage of ENCODE, and extend my compliments to the consortium for an amazingly well-coordinated effort to achieve an impressive level of consistency and quality for such a large consortium. Whatever else you might want to say about the idea of ENCODE, you cannot say that ENCODE was poorly executed.
It’s time to get into the interesting stuff – what’s actually in the papers. Among the results I’ve been most eagerly awaiting to see in print are the DNase hypersensitivity results now published in Thurman et al. (Nature 489, 75–82 (06 September 2012) doi:10.1038/nature11232)
Why is this interesting? Because it raises provocative and possibly disturbing questions regarding how transcription factors navigate and read out information from the genome....
Hat-tip @BoraZ
No comments:
Post a Comment