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Friday, May 31, 2019

The genetic nature of nurture


At Science magazine (open access)

Genetic variants provide a nurturing environment

Genetic variants in parents may affect the fitness of their offspring, even if the child does not carry the allele. This indirect effect is referred to as “genetic nurture.” Kong et al. used data from genome-wide association studies of educational attainment to construct polygenic scores for parents that only considered the nontransmitted alleles (see the Perspective by Koellinger and Harden). The findings suggest that genetic nurture is ultimately due to genetic variation in the population and is mediated by the environment that parents create for their children.

Science, this issue p. 424; see also p. 386

in The nature of nurture: Effects of parental genotypes
Augustine Kong and many others
Science 26 Jan 2018:
Vol. 359, Issue 6374, pp. 424-428
DOI: 10.1126/science.aan6877

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