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Wednesday, October 17, 2012

Natural GMOs Part 148. Jumping DNA rides aboard a virus, which targets a giant virus, which infects an amoeba, which infected a woman’s eye

Ed Yong on the seriously weird and real:
Earlier this year, a 17-year-old French woman arrived at her ophthalmologist with pain and redness in her left eye . She had been using tap water to dilute the cleaning solution for her contact lenses, and even though they were meant to be replaced every month, she would wear them for three. As a result, the fluid in her contact lens case had become contaminated with three species of bacteria, an amoeba called Acanthamoeba polyphaga that can caused inflamed eyes.
The mystery of the woman’s inflamed eyes was solved, but Bernard La Scola  and Christelle Desnues  looked inside the amoeba, they found more surprises.
It was carrying two species of bacteria, and a giant virus  that no one had seen before—they called it Lentille virus. Inside that, they found a virophage—an virus that can only reproduce in cells infected by other viruses—which they called Sputnik 2. And in both Lentille virus and Sputnik 2, they found even smaller genetic parasites – tiny chunks of DNA that can hop around the genomes of the virus, and stow away inside the virophage. They called these transpovirons....


Continues @ Jumping DNA rides aboard a virus, which targets a giant virus, which infects an amoeba, which infected a woman’s eye | Not Exactly Rocket Science | Discover Magazine:

Reference: Desnues, La Scola, Yutin, Fournous, Robert, Azza, Jardot, Monteil, Campocasso, Koonin & Raoult. 2012. Provirophages and transpovirons as the diverse mobilome of giant viruses. http://dx.doi.org/10.1073/pnas.1208835109


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